Anchored HTML File of EIDs

	WEB-based GEne SeT AnaLysis Toolkit

	*Translating gene lists into biological insights...*

User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for each enriched gene sets are listed in this table.
For each gene set, the first row lists database name, gene set name , and corresponding gene set ID.
The second row lists the following statistics:

C: the number of reference genes in the category
O: the number of genes in the gene set and also in the category
E: the expected number in the category
R: ratio of enrichment
rawP: p value from hypergeometric test
adjP: p value adjusted by the multiple test adjustment

Finally, genes in the pathway are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:KEGG pathway Name:Vascular smooth muscle contraction ID:04270
C=116; O=3; E=0.09; R=31.87; rawP=0.0001; adjP=0.0005
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000077157	NA	PPP1R12B	protein phosphatase 1, regulatory subunit 12B	4660	ENSG00000077157
2	ENSG00000140795	NA	MYLK3	myosin light chain kinase 3	91807	ENSG00000140795
3	ENSG00000138308	NA	PLA2G12B	phospholipase A2, group XIIB	84647	ENSG00000138308

Database:KEGG pathway Name:Complement and coagulation cascades ID:04610
C=69; O=2; E=0.06; R=35.72; rawP=0.0015; adjP=0.0037
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000198734	NA	F5	coagulation factor V (proaccelerin, labile factor)	2153	ENSG00000198734
2	ENSG00000039537	NA	C6	complement component 6	729	ENSG00000039537

Database:KEGG pathway Name:Toxoplasmosis ID:05145
C=132; O=2; E=0.11; R=18.67; rawP=0.0052; adjP=0.0087
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000168811	NA	IL12A	interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)	3592	ENSG00000168811
2	ENSG00000138308	NA	PLA2G12B	phospholipase A2, group XIIB	84647	ENSG00000138308

Database:KEGG pathway Name:Protein processing in endoplasmic reticulum ID:04141
C=165; O=2; E=0.13; R=14.94; rawP=0.0080; adjP=0.0100
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000140943	NA	MBTPS1	membrane-bound transcription factor peptidase, site 1	8720	ENSG00000140943
2	ENSG00000109501	NA	WFS1	Wolfram syndrome 1 (wolframin)	7466	ENSG00000109501

Database:KEGG pathway Name:Metabolic pathways ID:01100
C=1130; O=2; E=0.92; R=2.18; rawP=0.2333; adjP=0.2333
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000169255	NA	B3GALNT1	beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)	8706	ENSG00000169255
2	ENSG00000138308	NA	PLA2G12B	phospholipase A2, group XIIB	84647	ENSG00000138308

WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).